Tapering

The safest way to come off [Topamax](/drugs/topamax) (topiramate) is a slow, proportional taper: reduce by roughly 10% of your current dose at a time,...

The best symptom tracker for tapering is a simple daily log that scores your 5 worst symptoms from 0 to 10, records the date and size of every dose ch...

The safest way to come off [Depakote](/drugs/depakote) (valproate) is a slow, proportional taper of about 10% of your current dose every 4 weeks, with...

Nortriptyline withdrawal usually starts within 1 to 3 days of a dose reduction and is driven by cholinergic rebound, a wave of nausea, cramping, sweat...

Coming off Viibryd (vilazodone) usually feels like dizziness, nausea, brain zaps, and a short fuse, starting 2 to 4 days after a dose drop. Most peopl...

Fluvoxamine (Luvox) has one of the shortest half-lives of any SSRI, roughly 15 to 20 hours, which is why Luvox withdrawal often starts within a day or...

Trintellix (vortioxetine) withdrawal is milder than Effexor for most people, but it is not the "no discontinuation syndrome" drug the marketing sugges...

If your doctor refuses to help you taper, the single most effective next move is to put the request in writing and ask for a documented response. A wr...

Hello everyone. Today is day 1 on 10mg Prozac. My bio will give the details of all the drugs I've been on and am still on over the past couple years. ...

Stopping [Ritalin](/drugs/ritalin) or Concerta (methylphenidate) after regular use often triggers a rebound: crushing fatigue, flat mood, and a return...

Suboxone, the brand name combination of buprenorphine and naloxone, is one of the most effective medications for opioid use disorder, and one of the h...

[Lithium](/drugs/lithium), sold under the brand name Lithobid and generically as lithium carbonate, is one of the few psychiatric medications where st...

Buspirone, sold under the brand name Buspar, is an anxiolytic used for generalized anxiety disorder. Unlike benzodiazepines, it is not a controlled su...

Tracking withdrawal symptoms is one of the most useful things you can do while tapering off an antidepressant, and one of the most overlooked. Antidep...

Amitriptyline, sold under the brand name Elavil, is a tricyclic antidepressant (TCA) prescribed for depression, chronic pain, migraine prevention, and...

During my sertraline taper, I repeatedly observed an unexpected pattern: while reducing the dose continuously by approximately 0.5% per day, I experie...

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 I just want to say a heartfelt thank you to everyone who has spent years collecting, ...

Pregabalin, sold under the brand name [Lyrica](/drugs/lyrica), is prescribed for nerve pain, fibromyalgia, and generalized anxiety disorder, and it wo...

Zolpidem, sold under the brand name [Ambien](/drugs/ambien), is a "Z-drug" sedative-hypnotic prescribed for short-term insomnia. It is not a benzodiaz...

Adderall (mixed amphetamine salts) withdrawal happens because the brain has adjusted to a steady supply of extra dopamine and norepinephrine, and need...

Stopping [Vyvanse](/drugs/vyvanse) (lisdexamfetamine) after regular use often triggers a stimulant crash: exhaustion, flat mood, and a pull back towar...

Calculating a taper schedule means deciding how much of a dose to cut, and how often, without triggering withdrawal symptoms. The most common mistake ...

Hi, My first post/question on this forum. My son restarted his quetiapine taper 1 month ago. He came from 600 mg three years ago. He suffered PWS for...

Pristiq (desvenlafaxine) withdrawal has a reputation among patients and prescribers for being unusually rough, and the drug's own design is a big part...

Feeling okay. Been having bouts of fatigue and crying spells.

Feeling good. Been having bouts of appetite changes. The only side effects I get from Prozac are the three most common ones. Going next month to the...

Feeling good. I will speed up my appointment and suggest Zyprexa -25%. Next must be Depakote -50%, but I would not risk doing it that soon. I will si...

Hello everyone,I am opening this discussion to share my experience and connect with those who are at the same stage. I am 43 years old and I have just...

Feeling great. Been having bouts of nausea. Occasional heart racing but getting better after 10 days of dropping dose: