Question about updose

September 3, 2026

Anyone feel worse before they felt better after an updose? Crashed doing a liquid microtaper, tried to hold but couldn’t tolerate withdrawal so updosed trying to stabilize. On Day 3 of updose, I finally slept through the night and had a really good day on Day 4. Today is Day 5 and I only slept two hours again and having the worst body aches and burning sensation plus head pressure. For those that updosed, when did you feel like you turned a corner?

Zoloft —50 mg to 15 mg — 8 years with a cold turkey and reinstatement in between— was liquid micro tapering, crashed at 14.275 mg and now holding at 15 mg.

3 Replies

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CatinaSep 3

Community AnchorEffexor

Hi Maria, here is some information about stabilization if you're interested. I'm sure some others will chime in too! https://taper.community/thread/ff7ce496-025a-4391-95b4-cdd0063f092b

Venlafaxine (tapering) - Current dose 17.28 mg
Trazodone - 50 mg
Synthroid - 25 mcg

“Your brain and body know how to heal. Trust the process and keep going.”

Please Note: I am not a healthcare professional. Any advice given is based on personal experience and that of others in the lay withdrawal community.

Maria A.Sep 4

LighthouseZoloft · active

Thank you Catina- today has been much better. I think my body is finally starting to stabilize on my updose/hold.

Zoloft —50 mg to 15 mg — 8 years with a cold turkey and reinstatement in between— was liquid micro tapering, crashed at 14.275 mg and now holding at 15 mg.

⭐

CatinaSep 4

Community AnchorEffexor

"Thank you Catina- today has been much better. I think my body is finally starting to stabilize on my updose/hold." — @Maria A.

Oh what a relief! I'm glad to hear this Maria! Keep us posted on how you're doing. 🥰

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