Kindling? Hypersensitivity? Am I the Only One?

October 1, 2026··

Posted in:Miscellaneous Research & News Support Symptoms & Self-Care

I'm putting this out there for the sake of research. LOL. But I haven't seen this particular facet of the drugs mentioned in any forum or literature: side effects/withdrawal effects happening WITHOUT changing a dose. Part of my story is that as soon as a med reaches blood saturation and starts to "work" ( I was prescribed for insomnia...which wasn't event that bad in retrospect) I also get untenable side effects: restless legs frequent/chronic sinus infections GI symptoms I spent years getting MRI's and allergy tests (25 years!) while ALL ALONG it was the meds causing the symptoms. It happened no matter which SSRI I tried...and I think I've tried them all. Has anyone else encountered this or know anything about it? Thanks!

atypical in presentation of side effects, super sensitive to small doses and general delayed responder. never took a psych med that didn't' make me sick immediately with infections and restless legs. have never been able to tolerate being on them, but have never had support to get off so I've been bouncing back and forth. i don't like capital letters. sorry.

Paxil — 1 mg — 2 yrs — holding until Oct. 7 doc appt.
Seroquel — 50 — planning taper |
trileptal -75 planning taper
prasozin 1 mg planning taper

6 Replies

MamaLa1d ago

NavigatorProzac · holding

I have had flu like symptoms and GI symptoms for many years, since commencing SSRI’s….. multiple scopes and other tests. Dr’s have basically thrown their hands up not knowing what was happening. Pretty sure it’s been the ends all along as now that I am tapering and on a low dose, all of my symptoms are much improved except for right after a dose change where they ramp up again temporarily.

Prozac — 2.4mg — 4 — holding

anne noni moss1d ago

WelcomerPaxil · holding

thanks @MamaLa

HannaPot1d ago

WelcomerMirtazapine · active

Same with me. Wether I'm tapering or not. Every morning its that feeling of anxiety blurred vision and as if there is a hole on my brain. I also thought I am strugling with allergy, but end up to be this poison Mirtrazepam!

Mirtazapine — 30mg — 12weeks — actively tapering

anne noni moss1d ago

WelcomerPaxil · holding

Thank you so much @HannaPot 💓 I'm sure there are others like us. Thanks for adding to the "research "

Wolf1d ago

Community AnchorProzac · researching

Not really, once they are at a stable level they tend to work okay except that I had weird pauses and changes of manner in how Prozac works for me

Prozac — 40 mg — 6 months — holding | Zyprexa — 20 mg — 6 years — holding | Depakote — 600 mg — 8 months — **tapering** | Buspirone — 20 mg — 8 months — holding | with clinician
"If life is painful, start a rebellion and make it good."

anne noni moss1d ago

WelcomerPaxil · holding

thanks wolf!

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