Hi, I'm Holly D

October 19, 2026

Hi, I joined this community to help me on my tapering journey. I have bipolar disorder and over 3 years ago I was prescribed seroquel. My max dose was 300. I am now down to 150mg after experiencing too many side effects. Recently, heart issues. Hoping to gain some insight on how to come off this drug safely as I dont even tolerate the 25mg IR anymore that used to address my insomnia. Looking for help and support.

Seroquel — 150 — 3 years 6 months — holding | without clinician

1 Reply

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Catina3h ago

Community AnchorEffexor

Hi @Holly D, welcome to Taper Community! Long-term antipsychotic use can cause a myriad of health problems. I don't blame you for wanting to come off the Seroquel. You can read about Hyperbolic tapering in the Resources section. Have a look around the site, there's lots of helpful information. Also, if you search for the word "insomnia" you'll find lots of information. https://taper.community/resources/blog/quetiapine-seroquel-withdrawal-guide Wishing you the best with your taper! 🩷

Venlafaxine (tapering) - Current dose 17.28 mg
Trazodone - 50 mg
Synthroid - 25 mcg

“Your brain and body know how to heal. Trust the process and keep going.”

Please Note: I am not a healthcare professional. Any advice given is based on personal experience and that of others in the lay withdrawal community.

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