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Miscellaneous Zoloft (Sertraline)

October 16, 2026

I stopped taking Zoloft about 6 months ago. Didn’t really have any acute symptoms. Went on with my life without feeling much of a difference. I also have a heart arrhythmia (could very well be from the Zoloft for all I know) so I was taking a beta blocker with the Zoloft for years. At a physical my doctor recommended that I continue using the beta blocker to suppress some of the irregular beats and oh my what a mistake that was. Stress plus another drug that can pass through the blood brain barrier is apparently not a good combo when the brain is in a susceptible spot. Either way, I’ve welcomed the following symptoms into my life from one week on the beta blocker (now stopped).

Waking up in a panic most mornings
one night went from panic to nausea to profusely sweating in about 5 minutes.
insomnia
anxiety and major mood swings

It’s not always bad though. When I read about the waves and windows I was like YES that’s exactly it. I thought I maybe need to reinstate and go slower, but at this point I assume the acute effects of the drug have nothing to do with it. Once my brain heals, I’m done with this Zoloft scam forever. Peace and blessings to you all, AJNess

Zoloft — 0 — 4 years — completed taper | without clinician

2 Replies

RO24m ago

Have the symptoms gone once you stopped beta blocker or are you still experiencing the symptoms? I’m not sure if you can get withdrawal symptoms after 6 months. I tried Propranolol for my withdrawal symptoms but once was enough to put me off so I stopped it. It doesn’t really help inner restlessness, but made me feel like I was cogged up.

AJNess10m ago

Zoloft · completed

Unfortunately the symptoms are still alive and well after about a week of stopping. I used to take metoprolol and Zoloft at the exact same time everyday with no issues, but when I took the metoprolol alone it was not good. I usually have good hours during the day, sometimes a good night which is nice. However, the downs are pretty brutal. Even when I have nothing to be sad or anxious about, but my body says otherwise. I’m more sensitive to stress than I’ve ever been. Every morning I’ve been jolted awake by adrenaline. Just the one night was the adrenaline, then nausea then lying on the tile dripping sweat.

Zoloft — 0 — 4 years — completed taper | without clinician

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