Attn: maths brains / liquid taper experts - please help me!

September 30, 2026··

I have two issues, which I'll preface by saying that despite having three degrees, including a PhD, I am maths illiterate (I'm a language/word person - I do not do numbers), and this taper has been a huge challenge for my compromised brain, so please be gentle. Issue 1: Once I moved from pill cutting to liquid, around 3.75mg dose, I started on a 3mg/1ml ratio, then changed to a 1:1 ratio once I hit 1mg. Now that I'm approaching 0.1mg on the syringe and calculations have gotten trickier, I've moved to a 0.5mg/1ml ratio. That's made calculations and dosing easier, but I'm wondering what happens once I'm tapering below 0.01mg (my current dose is 0.12) and dosing gets even more challenging. Does anyone have any tips or tricks for that last leg for those of us who are planning to stop very low, e.g., around 0.04 or 0.02? Issue 2: I've been getting my liquid compounded cause I was anxious about messing the mix up or the suspension being less reliable homemade with water (and also having to do it very often). The expense of that was one reason I started pushing the river with my drops recently because I'm finding that now that I'm on such low doses, even the mix from the chemist is only good for 2 weeks (used to last much longer; I recall seeing people mention this happens at low doses on the SAD forum, so it's a thing). I'd love to do my own now to save the dosh, but I remain nervous about homemade water/pill suspension reliability, especially with Mirtazapine, given it doesn't dissolve. Is there anyone out there tapering off Mirt who feels really confident in their method and can share it with me?

Mirtazapine — 0.12mg — 3 years, 7 months — active, but temporary hold to stabilise

2 Replies

Polly's Farm1d ago

Trusted VoiceTrintellix · researching

I think you've done brilliantly to manage the dose and ratio changes so far! You might be better at maths than you think 🙂 Unfortunately, I can't help with either of your issues because I haven't got that low yet but I wanted to sympathise before someone with more experience comes along. Well done for getting this far and good luck with the rest of the taper!

Trintellix — 15mg — 4 years, 9 months — researching taper | Risperdal — 0.35mg — 4 years, 9 months — actively tapering | Depakine — 1000mg — 12 years — supporting others | with clinician

Mcat14h ago

Mirtazapine · holding

Thanks, that's very kind of you. I've certainly stepped up to the best of my ability in the maths dept - have had to. But I still struggle with it and lack confidence, and especially now that my brain is like mush at these lower doses, I'd really like some help. The local chemist has been really helpful, but I feel like there's a limit to how much you can pick someone's brain when they're not earning money from it.

Mirtazapine — 0.12mg — 3 years, 7 months — active, but temporary hold to stabilise

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