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Le-pendu

Tapering: Mirtazapine

10 posts

Northeast US

Im getting better but

August 4, 2026··
I just want to know. After this is over, is my brain always going to react to every stressor by completing numbing out? Especially joy and things like that?

Mirtazapine — 15 — 3 months | Lamictal — 25 | without clinician

12 Replies

Catina
CatinaStaff12d ago
Community AnchorEffexor
It's hard to say exactly how you're going to be affected once you're off the drug. I'm sure if you do have any residual symptoms they will slowly improve over time. That's what I've seen with many people.

Venlafaxine (tapering) - Current dose 17.92 mg
Trazodone - 50 mg
Levothyroxine - 25 mcg

“Your brain and body know how to heal. Trust the process and keep going.”

Please Note: I am not a healthcare professional. Any advice given is based on personal experience and that of others in the lay withdrawal community.

L
Le-pendu12d ago
WelcomerMirtazapine
Please. Actually read my question instead of vague answers. If you dont know just leave me alone. I am literally considering suicide can you not just play with my feelings.

Mirtazapine — 15 — 3 months | Lamictal — 25 | without clinician

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Wolf12d ago
Community AnchorProzac · researching
Remember, your body replaces 98% of its atoms within one year and it replaces 99,5% or more atoms within a few years.

Prozac — 40 mg — 6 months — holding | Zyprexa — 20 mg — 6 years — holding | Depakote — 600 mg — 8 months — **tapering** | Buspirone — 20 mg — 8 months — holding | with clinician
"If life is painful, start a rebellion and make it good."

W
Wolf12d ago
Community AnchorProzac · researching
I'm sorry for providing an AI response, but can have further research and confirmation. The exact nerve cells that do not change include: Cerebral Cortex Neurons: The cells responsible for memory, attention, perceptual awareness, thought, language, and consciousness. Cerebellar Neurons: Most of the neurons in your cerebellum, which govern balance, posture, and motor coordination. Retinal Ganglion and Photoreceptor Cells: The light-sensing rod and cone nerve cells in the back of your eye. Auditory Hair Cells: The specialized nerve cells in the organ of Corti (inner ear) that detect sound. Why These Cells Never Change Lack of Centrioles: Mature neurons lack centrioles, which are the cellular structures required to anchor and separate chromosomes during cell division. Circuit Preservation: Your brain functions as a massive, hardwired database. If cortical neurons constantly divided or swapped out their atoms, the physical synaptic pathways storing your long-term memories and learned behaviors would be erased. Survival Priority: Because these cells must last your entire life, mature neurons actively reprogram themselves to suppress the cellular "self-destruct" switch (apoptosis). They prioritize survival over everything else.

Prozac — 40 mg — 6 months — holding | Zyprexa — 20 mg — 6 years — holding | Depakote — 600 mg — 8 months — **tapering** | Buspirone — 20 mg — 8 months — holding | with clinician
"If life is painful, start a rebellion and make it good."

W
Wolf12d ago
Community AnchorProzac · researching
If the AI is right, of course, in short: you are very likely to get better with stressors. All that can be regained, but what is typically lost forever if lost, is basic function such as attention, response to stimulus as well as long-term memory, eyesight and hearing.

Prozac — 40 mg — 6 months — holding | Zyprexa — 20 mg — 6 years — holding | Depakote — 600 mg — 8 months — **tapering** | Buspirone — 20 mg — 8 months — holding | with clinician
"If life is painful, start a rebellion and make it good."

L
Le-pendu12d ago
WelcomerMirtazapine
@Wolf thank you. That does help a lot

Mirtazapine — 15 — 3 months | Lamictal — 25 | without clinician

Catina
CatinaStaff12d ago
Community AnchorEffexor
"Please. Actually read my question instead of vague answers. If you dont know just leave me alone. I am literally considering suicide can you not just play with my feelings." — @Le-pendu
I'm sorry @Le-pendu. I was just trying to help. Please hang in there.

Venlafaxine (tapering) - Current dose 17.92 mg
Trazodone - 50 mg
Levothyroxine - 25 mcg

“Your brain and body know how to heal. Trust the process and keep going.”

Please Note: I am not a healthcare professional. Any advice given is based on personal experience and that of others in the lay withdrawal community.

Catina
CatinaStaff12d ago
Community AnchorEffexor

Venlafaxine (tapering) - Current dose 17.92 mg
Trazodone - 50 mg
Levothyroxine - 25 mcg

“Your brain and body know how to heal. Trust the process and keep going.”

Please Note: I am not a healthcare professional. Any advice given is based on personal experience and that of others in the lay withdrawal community.

W
Wolf12d ago
Community AnchorProzac · researching
@Le-pendu happy to help. Our bodies have an amazing, truly incredible regeneration capacities that can fix just about anything that they could realistically fix. Still, only lizards can fix a lost limb. Keep in mind your ancestors also had their health troubles and injuries and they also had to survive and regenerate and withstand plenty of things in life circumstances worse than yours to become your ancestors.

Prozac — 40 mg — 6 months — holding | Zyprexa — 20 mg — 6 years — holding | Depakote — 600 mg — 8 months — **tapering** | Buspirone — 20 mg — 8 months — holding | with clinician
"If life is painful, start a rebellion and make it good."

W
Wolf12d ago
Community AnchorProzac · researching
@Le-pendu by the way, the only hopeless cases we are likely to get are with benzodiazepines and opiates. Your signature does not say anything about benzos.

Prozac — 40 mg — 6 months — holding | Zyprexa — 20 mg — 6 years — holding | Depakote — 600 mg — 8 months — **tapering** | Buspirone — 20 mg — 8 months — holding | with clinician
"If life is painful, start a rebellion and make it good."

W
Wolf11d ago
Community AnchorProzac · researching
@Le-pendu I looked into it even more. Apparently half of the brain may develop new neurons while other parts can't. But the good news for you is the area responsible for emotions actually keeps growing well into adulthood and possibly longer. There is not that much known for certain. The simple undisputed fact that 99% of our matter in our bodies is replaced should be enough to have some reassurance.

Prozac — 40 mg — 6 months — holding | Zyprexa — 20 mg — 6 years — holding | Depakote — 600 mg — 8 months — **tapering** | Buspirone — 20 mg — 8 months — holding | with clinician
"If life is painful, start a rebellion and make it good."

L
Le-pendu10d ago
WelcomerMirtazapine
@Wolf I was on clonazepam for a couple years but I stopped it as it was making me ill. But after stopping it I felt genuine progress. It wasn't until mirtazapine that I started to struggle. I've been on as as 4mg of clonazepam and stopped before and it did get bad. I was on it fir a year but it took three months to get better. Its almost 3 months now for the mirtazapine but I dont know. I noticed that things are not backsliding finally until today everything is horrible. It stopped getting worse end of July now idk what's happening

Mirtazapine — 15 — 3 months | Lamictal — 25 | without clinician

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