Hi, I'm Smilesbetter

November 10, 2026

Hi,was on 25mg Clomipromine,appx 30years.....As now on letrozole to prevent any lumps returning...I decided to come off of the former....I am finishing my first month of 10mg. I have been given another month of 10mg,to take as one every other night for two weeks ,then stop.I have really bad hot flushes ,more so in bed,and joint pain.I think this is to do with the letrozole.Is the dosage correct given by pharmacist at my Dr,s surgery?...Thanks...Jennifer Scott

Clomipramine — 25mg — 30years — actively tapering | without clinician

1 Reply

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Catina2d ago

Community AnchorEffexor

Hi @Smilesbetter, welcome to Taper Community! We don't recommend skipping days to taper; your brain needs as much consistency as possible. https://taper.community/resources/blog/every-other-day-dosing-tapering-risks If you go to the Symptoms and Self-Care section of the forum and click on the Guides tab, you'll find lots of helpful information and tips about how to deal with any withdrawal symptoms. What you're describing could be effects from withdrawing from your first drug. When did you start your new drug?

Venlafaxine (tapering) - Current dose 16.64 mg
Trazodone - 50 mg
Synthroid - 25 mcg

“Your brain and body know how to heal. Trust the process and keep going.”

Please Note: I am not a healthcare professional. Any advice given is based on personal experience and that of others in the lay withdrawal community.

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