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Tapering: Amitriptyline

researching

1 posts

UK

Hi, I'm JulieS

September 19, 2026ยทยท
I had a nervous breakdown 25 years ago and was prescribed Mirtazapine 50mg and Amitriptyline 50mg. I am extremely sensitive to the brand of Amitriptyline and when the brand I was used to became unavailable in 2018 and I was experiencing extreme side effects (which my doctors told me were not possible and did not exist!!!!) I decided to try and come off the mix of antidepressants. I went into the Priory treatment centre and was taken off both of these medications in 10 days. I was so, so ill to the point of being terrified, unable to sleep, speak, formulate thoughts/speech, sweats, nausea.......just unable to function to the point where I would have to take one of my children with me as my advocate. After 6 months of hell I decided to start taking Amitriptyline again and I stabilised somewhat. However, my insomnia returned and feeling really unwell became my every day norm. Strangely, when I have been prescribed Amitriptyline in Spain, the brand given to me, does not render me unwell. I have not been depressed for years so the only reason I continue to take Ami is because cessation is frightening and at 71 I fear the rest of my life will be blighted with mental/emotional and physical ill health. However, I don't feel so great right now either. It's a Catch 22 situation.

Amitriptyline โ€” 25mg โ€” 25 years โ€” researching taper

1 Reply

Catina
โญ
Catina1h ago
Community AnchorEffexor
Hi @JulieS, welcome to Taper Community. ๐Ÿฉท Thanks for sharing your story. You've been through a lot. I'm sorry you were taken off your meds so quickly, which caused you such severe withdrawal symptoms. I'm glad your children have been supportive of you in your times of need. Regarding your reactions to different brands...yes, switching brands/manufacturers can cause issues since they can contain different inactive ingredients and formulations. I'm glad you're doing your research and contemplating about how a future taper would look like for you. I know it's scary, but if you take things slowly with small reductions over a long period of time, then I think you can be free of it. I really do! We're here to support and guide you if and when you feel ready to taper the Amitriptyline. I'll provide some helpful links for you to mull over in the meantime: https://taper.community/drugs/amitriptyline https://taper.community/resources/blog/amitriptyline-withdrawal-and-tapering https://taper.community/thread/d41182b4-060b-4c2e-a1e8-da9e6777d7e5 https://taper.community/resources/blog/tapering-after-decades-use Catina ๐Ÿ’œ

Venlafaxine (tapering) - Current dose 17.92 mg
Trazodone - 50 mg
Levothyroxine - 25 mcg

โ€œYour brain and body know how to heal. Trust the process and keep going.โ€

Please Note: I am not a healthcare professional. Any advice given is based on personal experience and that of others in the lay withdrawal community.

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