Hi, I'm Jackjoe

Hi @Jackjoe, welcome to Taper Community! Your mom is fortunate to have your tender loving care. Can you provide a bit more detail about what doses she's been on the past 6 months? You want to make sure she's stable enough to be able to taper. We recommend Hyperbolic tapering here at Taper Community - monthly reductions of no more than 10% of the previous month's dose. The reductions will therefore get smaller and smaller as time goes on. The greatest changes in receptor occupancy happen at very low doses, so tapering this way is safer and easier on the brain. If you go to the Tapering Protocols, Symptoms & Self-Care, and I Need Support sections of the forum and click on the Guides tab, you'll find lots of helpful advice and tips. We'll await your response and look forward to helping you both. Catina 🌸

Hi Cantina, My mom is currently on 12.5 mg at night only. The highest dose she has ever been on was 12.5 around 3:00-4:00 and then 25 mg at night. I weaned her from 12.5 at 3:00 pm and slowly weaned evening dose down to 12.5. Honestly I feel that this drug is making her hallucinate more and making her extremely anxious, crying a lot. Her palliative doctor wants me to try a small dose of Lexapro. I have not started this yet, because I’m afraid of combo with seraquel. Any input appreciated! Tkx!

Thanks for providing more information. Did the hallucinations, anxiety, and crying happen after you reduced her dose? If so, they are most likely withdrawal symptoms, especially if a large reduction was made. It might be best to hold her dose for awhile until things stabilize a bit. Once that happens, you'll want to slowly taper off. We recommend Hyperbolic tapering here at Taper Community - monthly reductions of no more than 10% of the previous month's dose. The reductions will therefore get smaller and smaller as time goes on. The greatest changes in receptor occupancy happen at very low doses, so tapering this way is safer and easier on the brain. Also, if you go to the Symptoms and Self-Care section of the forum and click on the Guides tab, you'll find lots of helpful information and tips on how to deal with symptoms. Since you're supporting your dear mom, here is some information for you: https://taper.community/thread/ecea5d5c-ab7a-43f4-80b2-994bbee9fbf8 https://taper.community/drugs/seroquel https://taper.community/resources/blog/quetiapine-seroquel-withdrawal-guide Please let us know if you have any further questions and we'll help the best we can. 🩷