TaperCommunityTaperCommunity
M

Tapering: Zoloft

active

5 posts

California

Big differences between different taper calculations for sertraline

September 18, 2026··
Good morning ladies gentleman.Thank you for your assignments.I am on 68.75 mg sertraline.i wonder why when I do an automated taper calculation plan online in your site by 1% reduction of occupancy you give me a very tiny reduction of the dose from 68.75 to only 68.15 whereas in my calculation my starting dose of 68.75 mg corresponds by interpolation to approximately 82.61% SERT occupancy. Therefore: Start: 82.61% After 28 days: 81.61% After another 28 days: 80.61% etc. Using the Maudsley curve, 81.61% corresponds to about 60.87 mg. So an exact 1-percentage-point SERT reduction necessarily means approximately: 68.75 → 60.87 mg for the first step. your online taper said that I need more than two decades to reach zero while my own calculation it took only 6 years despite i measure the same interval of four weeks in the two methods.Then why this huge difference exists ? Thank you

Zoloft — 68.75 — 23 — actively tapering | without clinician

1 Reply

Based
BasedStaff3h ago
Community AnchorEffexor
Hey! Yes the taper calculator is only for absolute dose, not sert occupation. This leaves some issues, but is applicable for all drug classes where data is thin. Maybe i should try to add a sert occupational curve. Thanks for the input :)

Creator of Taper Community, here to help you.

Join the conversation

Sign in to share your experience and connect with others.

Need a clinician who understands tapering?

Browse our map of deprescribing-informed providers worldwide.

Find a Deprescriber